1. Meyer-Siegler, K., Mauro, D. J., Seal, G., Wurzer, J., deRiel, J. K., Sirover, M. A. A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase. Proc. Nat. Acad. Sci. 88: 8460-8464, 1991.
2. Zheng L, Roeder RG, Luo Y (2003). "S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component". Cell 114 (2): 255–66.
3. A. Tarze, A. Deniaud, M. Le Bras, E. Maillier, D. Molle, N. Larochette, N. Zamzami, G. Jan, G. Kroemer, and C. Brenner (2007). "GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization". Oncogene 26 (18): 2606–2620.
交叉反应: Human, mouse, rat
产品来源: Rabbit
产品别名: -
产品成分: -
检测范围: -
检测样品: -
产品应用: Western Blot (1:5000-10,000) Immunohistochemistry, IHC (1:100-500) Immunocytochemistry, ICC (1:50-200) Flow Cytometry (1:50-100) Other applications have not been tested. The optimal dilutions should be determined by end user.
保存条件: Aliquot and store at -20°C for 1 year. Avoid repeated freeze and thaw cycles.
背景资料: Glyceraldehyde 3-phosphate dehydrogenase (abbreviated as GAPDH or less commonly as G3PDH) is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. GAPDH has recently been implicated in several non-metabolic processes, including transcription activation, initiation of apoptosis, and ER to Golgi vesicle shuttling.
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免疫原 : -
